Problem:
When you log in you get an error that says the user profile service failed the sign on because the user profile cannot be loaded.
Resolution:
This typically happens because of a permissions issues on the Default folder.
- Browse to the folder by heading to \\SERVERNAME\C$\Users\Default
- Right click the folder and go to Security > Advanced
- From there, check the box at the bottom that says “Replace all child permission entries with inheritable permission entries from this object.”
Here’s a screenshot of that box:

That should take care of it. Let me know if this works for you.
Cheers!
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